Exploring neurocognition in psychiatric disorders

People

Franziska Knolle. I am a Marie Skłodowska-Curie Fellow at the Department of Neuroradiology, Klinikum rechts der Isar, Technichal Univeristy Munich. I am using the framework of predictive processing to understanding mental disorders, especially psychosis. I am investigating how potentially dysfunctional predictive processing links to psychiatric symptoms. I am particularly interested in the interaction between subcortical and cortical regions. In my research, I am using computational and machine learning approaches on fMRI and MEG/EEG as well as behavioural data to explore these topics.

I completed my PhD at the Max Planck Institute of Cognitive and Brain Science, Leipzig, Germany, with Sonja Kotz and Erich Schroeger on subcortical contributions to predictive processing in the sensory domain. After taking a break from active science to complete my medical undergrad (Physikum) at the TU Dresden, Dresden, Germany, I took up a post-doc position with Jenny Morton on animal models for Huntington’s Disease at PDN, University of Cambridge, Cambridge, UK. I then proceeded to work with Graham Murray and Paul Fletcher (both Psychiatry, University of Cambridge, Cambridge, UK) on understanding dysfunctional mechanisms underlying psychotic symptoms, using fMRI and computational approaches.

Current Master and Doctoral Students

Clara Seifert. Clara is looking at neural circuits of novelty and emotional salience processing in early early psychosis and Parkinson’s psychosis. (Master Thesis)

Elisabeth Sterner. Elisabeth is investigating the neural and temporal signatures of the use of prior knowledge during language processing in individuals with high schizotypy and autism using EEG. (Master Thesis)

Madeleine Seitz. Madeleine is studying cognitive and brain alterations in adolescents scoring high for prodromal psychosis using machine learning algorithms. (Master Thesis)

Pritha Sen. Pritha is exploring two-stage decision making in OCD, applying computational modelling. Furthermore, she is investigating alterations in white matter tractography in early psychosis.

Verena Demler. Verena is investigating the neural signatures of the use of prior knowledge during language processing in individuals with high schizotypy using fMRI and Magnetic Resonance Spectroscopy. (Medical Doctorate Thesis)

Sarah Daimer. In her successfully completed master’s project, she investigated the impact of the COVID-19 pandemic on mental health using machine learning approaches. She is further involved in mental health research in the lab.

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Summer students

Pritha Sen, LMU

Elisabeth Sterner, LMU

Omar Darawasha, TUM

Former lab members

Jolina Mueller-Chorus. She did her B.SC at the Albert-Ludwigs-Universität Freiburg, and is currently doing her M.SC. CLINICAL PSYCHOLOGY AND COGNITIVE NEUROSCIENCES at the Ludwig-Maximilian-Universität München. In her master’s project she investigated potential deficits in psychosis patients at different stages of the disease when using semantic prior information to decipher auditory input reduced in clarity (joined project with Clara Sowade), which she successfully completed in July 2021.

Clara Sowade. Clara completed her B.SC. PSYCHOLOGIE at the Ludwig-Maximilians-Universität München (LMU). She is currently doing her M.SC. CLINICAL PSYCHOLOGY AND COGNITIVE NEUROSCIENCES at the LMU. In her master’s project she investigated potential deficits in psychosis patients at different stages of the disease when using semantic prior information to decipher auditory input reduced in clarity (joined project with Jolina Mueller-Chorus), which she successfully completed in September 2021.

Collaborators

Dr Helen Blank (UKE Hamburg) – Prof Paul Fletcher (University of Cambridge) – Dr Olaf Hauk (MRC CBU) – Prof Sonja Kotz (Maastricht University) – Dr Lucy MacGregor (MRC CBU) – Dr Gemma Modinos (Kings College London) – Prof Jenny Morton (University of Cambridge) – Dr Graham Murray (University of Cambridge) – Dr Lisa Ronan (University of Cambridge) – Dr Christian Sorg (Technical University Munich) – Prof Roberto Viviani (University of Innsbruck)